WOCKHARDT LEAN SECRETS

anticholinergic/sedative combos decreases levels of promethazine by inhibition of GI absorption. Applies only to oral form of each agents. Use Caution/Watch.cimetidine will increase the stage or effect of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Warning/Watch. Prevents conversion of codeine to its active metabolite morphine.Promet